Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316171 | 0.84 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL27464533 | 0.79 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381252 | 0.79 | ADORA2A (0.82) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL11458747 | 0.78 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL3179304 | 0.77 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL10809926 | 0.77 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL10809922 | 0.77 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL8656014 | 0.77 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL315866 | 0.77 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL11458625 | 0.76 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207321-A | PROMOTES BLOOD PERFUSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |