Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 10/20 | 0.76 |
| ▸ | DRD2 | P14416 | 7/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | MTOR | P42345 | 3/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.76 |
| ▸ | THPO | P40225 | 3/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | BLM | P54132 | 3/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.74 |
| ▸ | GMNN | O75496 | 2/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14510732 | 0.87 | DRD1 (0.82) | DRD1DRD2MAPTHSD17B10MTOR | |
| SCHEMBL3516110 | 0.86 | DRD1 (1.00) | DRD1DRD2MAPTHSD17B10MTOR | |
| SCHEMBL29382672 | 0.86 | DRD1 (1.00) | DRD1DRD2MAPTHSD17B10MTOR | |
| SCHEMBL5945668 | 0.86 | DRD1 (1.00) | DRD1DRD2MAPTHSD17B10MTOR | |
| SCHEMBL11478102 | 0.85 | DRD1 (0.58) | DRD1DRD2MAPTHSD17B10MTOR | |
| Bromide SCHEMBL29634860 | 0.85 | DRD1 (1.00) | DRD1DRD2MAPTHSD17B10MTOR | |
| Bromide SCHEMBL11462466 | 0.84 | DRD1 (0.56) | DRD1DRD2MAPTHSD17B10MTOR | |
| SCHEMBL29389918 | 0.84 | DRD1 (1.00) | DRD1DRD2MAPTHSD17B10MTOR | |
| SCHEMBL29388918 | 0.84 | DRD1 (1.00) | DRD1DRD2MAPTHSD17B10MTOR | |
| SCHEMBL4388800 | 0.84 | DRD1 (1.00) | DRD1DRD2MAPTHSD17B10MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206210-A | PARKINSON'S DISEASE | SMITHKLINE CORPORATION (US) | 1980-06-03 | — | — | US | disclosed |