Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.71 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.71 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.71 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.71 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11219565 | 0.92 | MAPT (0.72) | MAPTTDP1NR1I2CTDSP1HPGD | |
| SCHEMBL11219562 | 0.92 | MAPT (0.72) | MAPTTDP1NR1I2CTDSP1HPGD | |
| SCHEMBL11531363 | 0.91 | MAPT (0.71) | MAPTTDP1NR1I2CTDSP1HPGD | |
| SCHEMBL11178495 | 0.91 | PTGS1 (0.78) | MAPTTDP1NR1I2CTDSP1HPGD | |
| SCHEMBL11840773 | 0.91 | MAPT (0.70) | MAPTTDP1NR1I2CTDSP1HPGD | |
| SCHEMBL11178499 | 0.91 | PTGS1 (0.78) | MAPTTDP1NR1I2CTDSP1HPGD | |
| SCHEMBL11503047 | 0.91 | PTGS1 (0.78) | MAPTTDP1NR1I2CTDSP1HPGD | |
| SCHEMBL11840763 | 0.91 | MAPT (0.70) | MAPTTDP1NR1I2CTDSP1HPGD | |
| SCHEMBL11444223 | 0.91 | MAPT (0.70) | MAPTTDP1NR1I2CTDSP1HPGD | |
| SCHEMBL11531408 | 0.89 | MAPT (0.68) | MAPTTDP1NR1I2CTDSP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4211703-A | CHEMICAL INTERMEDIATES FOR CEPHALOSPORINS | SMITHKLINE CORPORATION (US) | 1980-07-08 | — | — | US | disclosed |
| US-4189573-A | CHEMICAL INTERMEDIATES | SMITHKLINE CORPORATION (US) | 1980-02-19 | — | — | US | disclosed |
| US-4178288-A | Sulfaminoalkyl substituted tetrazole thiol intermediates for preparing cephalosporins | SMITHKLINE CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |
| US-4171368-A | 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4171362-A | 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4171433-A | 7-Amino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporin intermediates for preparing 7-acylamino cephalosporins | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4159373-A | 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins | SMITHKLINE CORPORATION (US) | 1979-06-26 | — | — | US | disclosed |
| US-4140694-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |
| US-4139701-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1979-02-13 | — | — | US | disclosed |
| US-4138556-A | ANTIBIOTICS, BACTERICIDES | SMITHKLINE CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
| US-4101656-A | 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4096256-A | ANTIBIOTICS | SMITHKLINE CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |
| US-4093723-A | ANTIBIOTICS | SMITHKLINE CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4068073-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067880-A | SULFOALKYL-OXADIAZOLE THIOLS | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4066761-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4059591-A | Ureidoalkyl substituted tetrazole thiol intermediates for preparing cephalosporins | SMITHKLINE CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |
| US-4048311-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4041162-A | ANTIBIOTICS, BACTERICIDES | SMITHKLINE CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4025626-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |