Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.36 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.33 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.32 |
| ▸ | APEX1 | P27695 | 3/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184717 | 0.89 | NR1I2 (0.40) | NR1I2PGRMAPTPPARGSLC22A6 | |
| SCHEMBL11566423 | 0.88 | NR1I2 (0.33) | NR1I2PGRMAPTPPARGSLC22A6 | |
| SCHEMBL11312162 | 0.88 | NR1I2 (0.37) | NR1I2PGRMAPTPPARGSLC22A6 | |
| SCHEMBL11423218 | 0.87 | NR1I2 (0.38) | NR1I2PGRMAPTPPARGSLC22A6 | |
| SCHEMBL9601254 | 0.83 | NR1I2 (0.34) | NR1I2PGRMAPTPPARGSLC22A6 | |
| SCHEMBL11466816 | 0.83 | NR1I2 (0.49) | NR1I2PGRMAPTPPARGSLC22A6 | |
| SCHEMBL11466815 | 0.83 | NR1I2 (0.49) | NR1I2PGRMAPTPPARGSLC22A6 | |
| SCHEMBL9600902 | 0.82 | NR1I2 (0.33) | NR1I2PGR | |
| SCHEMBL11194412 | 0.81 | NR1I2 (0.41) | NR1I2PGRMAPTPPARGSLC22A6 | |
| SCHEMBL11523021 | 0.81 | NR1I2 (0.46) | NR1I2PGRMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002605-B1 | CEPHALOSPORIN COMPOUNDS AND FORMULATIONS CONTAINING THEM FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS AND THE PREPARATION OF THE CEPHALOSPORIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| EP-0002605-A1 | Cephalosporin compounds and formulations containing them for use in the treatment of bacterial infections and the preparation of the cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |