Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.45 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL11484609 | 0.98 | CTBP2 (0.56) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 | |
| SCHEMBL29631318 | 0.96 | AKR1B1 (0.61) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 | |
| SCHEMBL2528595 | 0.96 | AKR1B1 (0.61) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 | |
| SCHEMBL8285 | 0.96 | AKR1B1 (0.61) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL22042026 | 0.94 | CTBP2 (0.59) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 | |
| SCHEMBL28532359 | 0.94 | CTBP2 (0.59) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 | |
| SCHEMBL30961703 | 0.94 | CTBP2 (0.59) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 | |
| Methyl Alcohol SCHEMBL9629191 | 0.94 | CTBP2 (0.59) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2527505 | 0.94 | CTBP2 (0.59) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 | |
| Water SCHEMBL30372687 | 0.94 | CTBP2 (0.59) | CTBP2PTGS2AKR1B1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198506-A | INTERMEDIATES FOR THE CORRESPONDING 3-SUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACIDS | BRISTOL-MYERS COMPANY (US) | 1980-04-15 | — | — | US | disclosed |
| US-4151352-A | CEPHALOSPORINS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4100346-A | Certain 7(o-amino-methyl- or methylaminomethylphenyl- or cyclohexadienyl- or thienylacetamide)-3[1-carboxymethyl-(or ethyl- or propyl-)-tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids | BRISTOL-MYERS COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4082912-A | ANTIBACTERIAL | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |