Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584101 | 0.81 | NR4A1 (0.57) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL11508509 | 0.81 | CYP2D6 (0.43) | PPARGPPARALMNACYP1A2L3MBTL1 | |
| SCHEMBL5042659 | 0.80 | MAOB (0.56) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL11482361 | 0.77 | KMT2A (0.54) | NR4A2ALOX5MAOBFFAR1SRD5A2 | |
| SCHEMBL10560921 | 0.77 | BCHE (0.52) | ALOX5LMNAACACBFFAR1 | |
| SCHEMBL10560914 | 0.77 | BCHE (0.52) | ALOX5LMNAACACBFFAR1 | |
| SCHEMBL7761599 | 0.76 | NR4A1 (0.62) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL10999770 | 0.76 | NR4A1 (0.62) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL10583095 | 0.76 | NR4A1 (0.54) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL27733432 | 0.76 | NR4A1 (0.57) | PPARGPPARANR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007716-A1 | R-N-(2-phenyl-2-hydroxyethyl)-3-phenylpropyl amines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-02-06 | — | — | EP | disclosed |