Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.60 |
| ▸ | PREP | P48147 | 1/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465428 | 0.98 | DPP4 (0.62) | DPP4PREPDPP8DPP9CHRM2 | |
| SCHEMBL1239549 | 0.98 | DPP4 (0.62) | DPP4PREPDPP8DPP9CHRM2 | |
| Hydrochloric Acid SCHEMBL27511587 | 0.96 | DPP4 (0.60) | DPP4PREPDPP8DPP9CHRM2 | |
| Hydrochloric Acid SCHEMBL5964647 | 0.96 | DPP4 (0.60) | DPP4PREPDPP8DPP9CHRM2 | |
| Hydrochloric Acid SCHEMBL5964641 | 0.96 | DPP4 (0.60) | DPP4PREPDPP8DPP9CHRM2 | |
| Ammonia Solution, Strong SCHEMBL27597606 | 0.96 | DPP4 (0.60) | DPP4PREPDPP8DPP9CHRM2 | |
| SCHEMBL11451025 | 0.94 | CHRM2 (0.55) | DPP4PREPDPP8DPP9CHRM2 | |
| SCHEMBL11820231 | 0.92 | CHRM2 (0.57) | DPP4PREPDPP8DPP9CHRM2 | |
| SCHEMBL1819999 | 0.80 | CHRM2 (0.56) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2269972 | 0.80 | CHRM2 (0.56) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008802-A1 | Ergoline derivatives, their preparation and therapeutic composition containing them | FARMITALIA CARLO ERBA S.p.A. (IT) | 1980-03-19 | — | — | EP | disclosed |