Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.64 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039115 | 0.83 | POLB (0.67) | ARCACNA1BAPBA1RAB9APOLB | |
| SCHEMBL11119003 | 0.82 | CACNA1B (0.49) | ARCACNA1BAPBA1LMNAHTT | |
| SCHEMBL11461814 | 0.81 | AR (0.64) | ARPGRMEN1KMT2AALDH1A1 | |
| SCHEMBL11469297 | 0.81 | AR (0.64) | ARLMNAPGRMEN1TP53 | |
| SCHEMBL12386350 | 0.81 | AR (0.64) | ARLMNAPGRMEN1TP53 | |
| SCHEMBL13913495 | 0.81 | AR (0.64) | ARLMNAPGRMEN1TP53 | |
| SCHEMBL31330678 | 0.81 | AR (0.64) | ARLMNAPGRMEN1TP53 | |
| SCHEMBL11726412 | 0.81 | AR (0.55) | ARLMNAPGRMEN1TP53 | |
| SCHEMBL11465842 | 0.81 | AR (0.68) | ARCACNA1BAPBA1LMNAPGR | |
| SCHEMBL11480812 | 0.81 | AR (0.68) | ARLMNAPGRMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234736-A | FLUOROPHENYL DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1980-11-18 | — | — | US | disclosed |