SCHEMBL11470947

SCHEMBL11470947

CCOC(C)(C)COC1CCNCC1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31
HTR7 P34969 1/20 0.31
HTR2B P41595 1/20 0.31
HTR3A P46098 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HTR4 Q13639 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11472544 0.81 SLC6A2 (0.33) SLC6A2HTR2AHTR2CSLC6A4HTR7
SCHEMBL19023307 0.78 SLC6A2 (0.35) SLC6A2HTR2AHTR2CSLC6A4HTR7
SCHEMBL78025 0.75
SCHEMBL11312585 0.75 SLC6A2 (0.33) SLC6A2HTR2AHTR2CSLC6A4HTR7
SCHEMBL3665088 0.75 SLC6A2 (0.33) SLC6A2HTR2AHTR2CSLC6A4HTR7
SCHEMBL470884 0.75 SLC6A2 (0.33) SLC6A2HTR2AHTR2CSLC6A4HTR7
SCHEMBL11470301 0.74 HRH1 (0.41) SLC6A2HTR2AHTR2CSLC6A4HTR7
Hydrochloric Acid SCHEMBL2775512 0.73 SLC6A2 (0.37) SLC6A2HTR2AHTR2CSLC6A4HTR7
SCHEMBL408304 0.70 HTR2C (0.35) SLC6A2HTR2AHTR2CSLC6A4HTR7
SCHEMBL29013690 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4237138-A REGULATORS OF CARDIOVASCULAR SYSTEM PFIZER INC. (US) 1980-12-02 US disclosed