Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 1/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.42 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.42 |
| ▸ | AMY2A | P04746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2691427 | 0.99 | IGF2R (0.44) | IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL1134654 | 0.97 | IGF2R (0.43) | IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL6651759 | 0.97 | IGF2R (0.43) | IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL8884633 | 0.96 | IGF2R (0.47) | IGF2RLGALS8LGALS3LGALS4AMY2A | |
| Water SCHEMBL21777653 | 0.96 | IGF2R (0.42) | IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL8885773 | 0.96 | IGF2R (0.47) | IGF2RLGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL8884277 | 0.93 | IGF2R (0.48) | IGF2RLGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL8883154 | 0.93 | IGF2R (0.48) | IGF2RLGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL346230 | 0.92 | IGF2R (0.43) | IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL8883415 | 0.89 | IGF2R (0.44) | IGF2RLGALS8LGALS3LGALS4AMY2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3628 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999504-A1 | POLYMORPHIC FORMS OF (R)-4-(1-((3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)SULFONYL)-1-FLUOROETHYL)-N-(ISOXAZOL-3-YL)PIPERIDINE-1-CARBOXAMIDE | MyoKardia, Inc. (US) | 2022-05-25 | — | — | EP | claimed |
| CN-114127061-A | Polymorphic forms of (R) -4- (1- ((3- (difluoromethyl) -1-methyl-1H-pyrazol-4-yl) sulfonyl) -1-fluoroethyl) -N- (isoxazol-3-yl) piperidine-1-carboxamide | 迈奥卡迪亚公司 | 2022-03-01 | — | — | CN | claimed |
| WO-2021011586-A1 | POLYMORPHIC FORMS OF (R)-4-(1-((3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)SULFONYL)-1-FLUOROETHYL)-N-(ISOXAZOL-3-YL)PIPERIDINE-1-CARBOXAMIDE | MyoKardia, Inc. (US) | 2021-01-21 | — | — | WO | claimed |
| EP-3892116-B1 | COMPOSITION | OPTIBIOTIX LTD (GB) | 2026-04-01 | — | — | EP | disclosed |
| US-12042513-B2 | Proteolysis targeting chimeric molecules (PROTACs) with functional handles and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-23 | — | — | US | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-07-18 | — | — | US | disclosed |
| EP-4398923-A1 | ENGINEERED PHENYLALANINE AMMONIA LYASE ENZYMES | Ginkgo Bioworks, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-118324762-A | Compounds and compositions for treating CNS disorders | 布鲁奥科制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240226203-A9 | COMPOSITIONS AND METHODS OF TREATING HUNTINGTON'S DISEASE | VOYAGER THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240226026-A1 | BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ARES CAPITAL CORPORATION, AS AGENT | 2024-07-11 | — | — | US | disclosed |
| WO-2008070538-A2 | MICELLAR NANOPARTICLES COMPRISING BOTULINUM TOXIN | ANTERIOS, INC. (US) | 2008-06-12 | — | — | WO | disclosed |
| WO-2008063300-A2 | BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063933-A2 | PAK MODULATORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008060448-A2 | SMALL MOLECULE PAK INHIBITORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008028057-A2 | SHIKIMIC ACID-DERIVED COMPOUNDS FOR INHIBITION AND DETECTION OF AURORA A-ASSOCIATED TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2007106415-A9 | TRIGGERED SELF-ASSEMBLY CONJUGATES AND NANOSYSTEMS | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007137117-A2 | APTAMER-DIRECTED DRUG DELIVERY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007106415-A2 | TRIGGERED SELF-ASSEMBLY CONJUGATES AND NANOSYSTEMS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007042745-A1 | CHOCOLATE BASED APPETITE SUPPRESSANT | ZUMBE ALBERT (GB) | 2007-04-19 | — | — | WO | disclosed |