Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.66 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.66 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.66 |
| ▸ | ALB | P02768 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | SNCA | P37840 | 1/20 | 0.64 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | APEX1 | P27695 | 3/20 | 0.59 |
| ▸ | APAF1 | O14727 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472490 | 1.00 | NR1I2 (0.69) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL8869035 | 0.91 | NR1I2 (0.83) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL8869018 | 0.91 | NR1I2 (0.83) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL13900618 | 0.91 | NR1I2 (0.83) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL8867830 | 0.90 | TDP1 (0.73) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL8867820 | 0.90 | TDP1 (0.73) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL11391493 | 0.90 | TDP1 (0.73) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL11478735 | 0.89 | NR1I2 (0.74) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL11473296 | 0.89 | NR1I2 (0.84) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL11478765 | 0.89 | NR1I2 (0.74) | NR1I2HTR2CPPARGMAPTSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018155-A2 | Novel cephalosporin compounds, a process for the preparation thereof, pharmaceutical compositions containing the same and the use thereof as a therapeutic agent against a microorganism | NOVO NORDISK A/S (DK) | 1980-10-29 | — | — | EP | disclosed |