Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.77 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.75 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8261934 | 0.88 | DNMT3A (0.84) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL4654636 | 0.87 | DNMT3A (0.82) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL29808416 | 0.87 | DNMT3A (1.00) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11358623 | 0.87 | DNMT3A (0.82) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL1144242 | 0.87 | DNMT3A (1.00) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL18029599 | 0.87 | DNMT3A (0.82) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11481619 | 0.87 | HDAC1 (0.83) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11481623 | 0.87 | HDAC1 (0.83) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11474063 | 0.86 | DNMT3A (0.69) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11474059 | 0.86 | DNMT3A (0.69) | DNMT3AHDAC1HDAC6NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238506-A | SECONDARY OR TERTIARY AMIDE-SUBSTITUTED | BOEHRINGER MANNHEIM GMBH (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4113871-A | HYPOGLYCEMICALLY AND HYPOLIPIDEMICALLY ACTIVE DERIVATIVES OF PHENYL-ALKANE-CARBOXYLIC ACIDS | BOEHRINGER MANNHEIM GMBH (DE) | 1978-09-12 | — | — | US | disclosed |