Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | TTR | P02766 | 1/20 | 0.69 |
| ▸ | PPOX | P50336 | 1/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113819 | 0.91 | TDP1 (0.69) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL25396918 | 0.88 | TDP1 (0.70) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11482745 | 0.88 | TDP1 (0.70) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9768703 | 0.88 | TDP1 (0.73) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10775940 | 0.87 | MEN1 (0.71) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10993354 | 0.87 | MEN1 (0.74) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11071008 | 0.87 | MEN1 (0.71) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10991967 | 0.86 | TDP1 (0.77) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10994712 | 0.86 | TDP1 (0.70) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11113824 | 0.86 | MEN1 (0.70) | TDP1KMT2AMEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209318-A | Herbicidal esters of 4-trifluoromethyl-3-carboxamido-4-nitro diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1980-06-24 | — | — | US | disclosed |