Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474805 | 1.00 | IDO1 (0.41) | IDO1KMT2AMEN1ENPP2FAAH | |
| SCHEMBL11247074 | 1.00 | IDO1 (0.41) | IDO1KMT2AMEN1ENPP2FAAH | |
| SCHEMBL11255560 | 0.94 | KMT2A (0.42) | IDO1KMT2AMEN1FAAHKDM4E | |
| SCHEMBL11486578 | 0.94 | KMT2A (0.42) | IDO1KMT2AMEN1FAAHKDM4E | |
| SCHEMBL11472122 | 0.94 | KMT2A (0.42) | IDO1KMT2AMEN1FAAHKDM4E | |
| SCHEMBL11254332 | 0.87 | SMPD1 (0.43) | IDO1KMT2AMEN1FAAHKDM4E | |
| SCHEMBL11483435 | 0.87 | SMPD1 (0.43) | IDO1KMT2AMEN1FAAHKDM4E | |
| SCHEMBL11489363 | 0.87 | SMPD1 (0.43) | IDO1KMT2AMEN1FAAHKDM4E | |
| SCHEMBL11482014 | 0.86 | TRPV1 (0.40) | IDO1KMT2AMEN1TRPV1 | |
| SCHEMBL11253871 | 0.86 | TRPV1 (0.40) | IDO1KMT2AMEN1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238501-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4237162-A | MITICIDES, LARVACIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |