Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.84 |
| ▸ | GSK3B | P49841 | 11/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15114347 | 0.96 | PTPN1 (0.78) | PTPN1GSK3BSMN1; SMN2HPGDKDM4E | |
| SCHEMBL29411099 | 0.92 | PTPN1 (1.00) | PTPN1GSK3BSMN1; SMN2HPGDKDM4E | |
| SCHEMBL220588 | 0.92 | PTPN1 (1.00) | PTPN1GSK3BSMN1; SMN2HPGDKDM4E | |
| SCHEMBL203507 | 0.90 | PTPN1 (0.70) | PTPN1GSK3B | |
| SCHEMBL10969669 | 0.88 | PTPN1 (0.68) | PTPN1GSK3BSMN1; SMN2HPGDKDM4E | |
| SCHEMBL2758624 | 0.88 | PTPN1 (0.68) | PTPN1GSK3BSMN1; SMN2HPGDKDM4E | |
| SCHEMBL1293480 | 0.88 | PTPN1 (0.68) | PTPN1GSK3BSMN1; SMN2HPGDKDM4E | |
| SCHEMBL12520199 | 0.88 | PTPN1 (0.68) | PTPN1GSK3BSMN1; SMN2HPGDKDM4E | |
| SCHEMBL31065275 | 0.85 | GSK3B (0.71) | PTPN1GSK3BSMN1; SMN2HPGDKDM4E | |
| SCHEMBL10415427 | 0.85 | PTPN1 (0.64) | PTPN1GSK3BSMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052542-A | HALO-ACETYL HIGH GREEN STRENGTH RUBBERS | POLYSAR LIMITED (CA) | 1977-10-04 | — | — | US | claimed |
| US-4222906-A | ADDING THE CATIONIC POLYMER DURING A SECOND STAGE OF MIXING | POLYSAR LIMITED (CA) | 1980-09-16 | — | — | US | disclosed |