Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13631010 | 1.00 | EPHX1 (0.42) | EPHX1CASP2KDM1AZDHHC20ZDHHC2 | |
| SCHEMBL14996213 | 0.98 | KDM1A (0.40) | EPHX1CASP2KDM1AZDHHC20ZDHHC2 | |
| SCHEMBL13488627 | 0.93 | KDM1A (0.41) | EPHX1KDM1AMGLL | |
| SCHEMBL22645875 | 0.85 | MCL1 (0.39) | KDM1A | |
| SCHEMBL25615703 | 0.84 | EPHX1 (0.42) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL11192769 | 0.83 | KDM1A (0.37) | KDM1A | |
| SCHEMBL10567473 | 0.82 | PAOX (0.40) | KDM1A | |
| SCHEMBL1151570 | 0.81 | EPHX1 (0.37) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL21477744 | 0.79 | KDM1A (0.37) | KDM1A | |
| SCHEMBL13617152 | 0.79 | KDM1A (0.37) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212875-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-07-15 | — | — | US | disclosed |