Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6123091 | 0.77 | — | — | |
| SCHEMBL1199563 | 0.71 | EPHX1 (0.52) | TSHREPHX1CYP2C19MEN1KMT2A | |
| SCHEMBL1103798 | 0.71 | EPHX1 (0.52) | TSHREPHX1CYP2C19MEN1KMT2A | |
| SCHEMBL63809 | 0.71 | EPHX1 (0.52) | TSHREPHX1CYP2C19MEN1KMT2A | |
| SCHEMBL3644410 | 0.71 | EPHX1 (0.52) | TSHREPHX1CYP2C19MEN1KMT2A | |
| SCHEMBL12914371 | 0.71 | EPHX1 (0.52) | TSHREPHX1CYP2C19MEN1KMT2A | |
| SCHEMBL1199046 | 0.71 | EPHX1 (0.52) | TSHREPHX1CYP2C19MEN1KMT2A | |
| SCHEMBL270441 | 0.71 | EPHX1 (0.52) | TSHREPHX1CYP2C19MEN1KMT2A | |
| SCHEMBL11573778 | 0.69 | TSHR (0.39) | TSHRCYP2C19MAOAMAOBKDM1A | |
| SCHEMBL6570141 | 0.69 | EPHX1 (0.50) | TSHREPHX1CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228254-A | ONE PACKAGE CURE SYSTEM OF A TACK-FREE ELASTOMER | EXXON RESEARCH & ENGINEERING CO. (US) | 1980-10-14 | — | — | US | disclosed |