Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12147804 | 0.81 | GRM5 (0.53) | GRM5CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7940218 | 0.79 | GRM5 (0.59) | GRM5CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL11474709 | 0.78 | GRM5 (0.57) | GRM5CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL22043408 | 0.77 | CA12 (0.47) | MAOAMAOBACHEGSTP1CA12 | |
| SCHEMBL5704167 | 0.76 | CA12 (0.63) | MAOAMAOBACHEGSTP1CA12 | |
| SCHEMBL2669046 | 0.75 | NQO1 (0.56) | GRM5CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL384212 | 0.75 | MAOB (0.56) | GRM5MAOAMAOBACHEGSTP1 | |
| SCHEMBL17672869 | 0.74 | KMT2A (0.46) | GRM5CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL31390543 | 0.74 | MAOB (0.41) | MAOAMAOBACHEGSTP1CA12 | |
| Hydrochloric Acid SCHEMBL21694040 | 0.74 | CA12 (0.61) | MAOAMAOBACHEGSTP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119499407-A | Fe-based T7 peptide targeted brain glioma micromolecular magnetic resonance contrast agent and preparation and synthesis method and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2025-02-25 | — | — | CN | disclosed |
| US-11117863-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-09-14 | — | — | US | disclosed |
| US-20200172486-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-4220577-A | Iodopropargyl pyridyl and picolinyl ethers and thioethers as paint fungicides | GIVAUDAN CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |
| US-4170704-A | STABLE TO HEAT AND LIGHT | GIVAUDAN CORPORATION (US) | 1979-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | GRM5 690/4885MAOA 1046/4885MAOB 793/4885 |
| US-20200172486-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CBR3, CBR1 | GRM5 1405/4885MAOA 262/4885MAOB 241/4885 |
| US-11117863-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CBR3, CBR1 | GRM5 1405/4885MAOA 262/4885MAOB 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.