Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.55 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.49 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11839032 | 0.93 | GSTP1 (0.52) | MCL1BCL2A1GSTP1GSTM2CA12 | |
| SCHEMBL30468979 | 0.87 | MEN1 (0.49) | GSTP1GSTM2MAPK1TSHRTDP1 | |
| SCHEMBL11483285 | 0.87 | MEN1 (0.49) | GSTP1GSTM2MAPK1TSHRTDP1 | |
| SCHEMBL1538922 | 0.81 | MAPT (0.56) | CA12CA1CA2CA7CA13 | |
| SCHEMBL11962582 | 0.81 | TDP1 (0.50) | CA12CA1CA2CA7CA13 | |
| SCHEMBL31038411 | 0.78 | MAPT (0.54) | MAPK1TSHRTDP1MAOAMAOB | |
| SCHEMBL6677640 | 0.78 | MAPT (0.54) | MAPK1TSHRTDP1MAOAMAOB | |
| SCHEMBL2419394 | 0.77 | PDE7A (0.56) | GSTP1GSTM2MAPK1TSHRTDP1 | |
| SCHEMBL11483675 | 0.77 | MAPT (0.54) | MAPK1TSHRTDP1MAPTALDH1A1 | |
| SCHEMBL3862471 | 0.77 | APEX1 (0.50) | MAPK1TSHRTDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4185018-A | Process for producing benzofurazan-1-oxides | CIBA-GEIGY CORPORATION (US) | 1980-01-22 | — | — | US | disclosed |