Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 5/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862379 | 1.00 | PTGER2 (0.45) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11862363 | 1.00 | PTGER2 (0.45) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11862373 | 1.00 | PTGER2 (0.45) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11868943 | 0.93 | MEN1 (0.40) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11868949 | 0.93 | MEN1 (0.40) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11868941 | 0.93 | MEN1 (0.40) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11719721 | 0.90 | PTGER2 (0.55) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11865876 | 0.89 | PTGER2 (0.53) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11865889 | 0.89 | PTGER2 (0.53) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11865880 | 0.89 | PTGER2 (0.53) | PTGER2PTGER4PTGER3MEN1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209444-A | INHIBITORS OF AGGREGATION OR ADHESION OF THROMBOCYTES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-06-24 | — | — | US | disclosed |