Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488776 | 0.95 | HDAC6 (0.65) | HDAC6MAPTTSHRMAPK1KDM4E | |
| SCHEMBL11487087 | 0.91 | MAPT (0.65) | HDAC6MAPTTSHRMAPK1KDM4E | |
| SCHEMBL11245183 | 0.91 | HDAC6 (0.69) | HDAC6MAPTTSHRMAPK1KDM4E | |
| SCHEMBL1355587 | 0.89 | HDAC6 (0.77) | HDAC6MAPTTSHRMAPK1KDM4E | |
| SCHEMBL11245864 | 0.87 | MAPT (0.73) | HDAC6MAPTTSHRMAPK1KDM4E | |
| SCHEMBL9445894 | 0.86 | MAPT (0.70) | HDAC6MAPTTSHRMAPK1KDM4E | |
| SCHEMBL7952900 | 0.85 | HDAC6 (0.62) | HDAC6MAPTTSHRMAPK1KDM4E | |
| SCHEMBL27516230 | 0.85 | HDAC6 (0.67) | HDAC6MAPTTSHRKDM4EPOLB | |
| SCHEMBL20918131 | 0.84 | HDAC6 (0.69) | HDAC6MAPTTSHRKDM4EPOLB | |
| SCHEMBL7956506 | 0.84 | HDAC6 (0.65) | HDAC6MAPTTSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239903-A | ANTISPASMODIC AGENTS | DAIICHI SEIYAKU CO., LTD. (JP) | 1980-12-16 | — | — | US | disclosed |