Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17574696 | 0.77 | TSHR (0.46) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL839301 | 0.76 | TSHR (0.48) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL11495312 | 0.76 | TSHR (0.48) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL19162068 | 0.74 | TSHR (0.43) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL11484858 | 0.73 | TSHR (0.42) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL11486030 | 0.73 | TSHR (0.39) | TSHRGSK3AGSK3B | |
| SCHEMBL11484084 | 0.73 | TSHR (0.39) | TSHRGSK3AGSK3B | |
| SCHEMBL29304531 | 0.69 | TSHR (0.46) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL10702274 | 0.69 | TSHR (0.50) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL181570 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189587-A | CORROSION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1980-02-19 | — | — | US | disclosed |