Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486638 | 1.00 | TNKS (0.55) | TNKSMAOBARCA9CA1 | |
| SCHEMBL3979428 | 0.91 | TNKS (0.63) | TNKSMAOBARCA9CA1 | |
| SCHEMBL11500108 | 0.87 | MAOB (0.43) | TNKSMAOBARCA9CA1 | |
| SCHEMBL11500109 | 0.87 | MAOB (0.43) | TNKSMAOBARCA9CA1 | |
| SCHEMBL11493389 | 0.86 | TNKS (0.46) | TNKSMAOBARCA9KDM4E | |
| SCHEMBL11493391 | 0.86 | TNKS (0.46) | TNKSMAOBARCA9KDM4E | |
| SCHEMBL11486060 | 0.85 | MAOB (0.62) | MAOBCA9CA1CA2ALOX5 | |
| SCHEMBL11486058 | 0.85 | MAOB (0.62) | MAOBCA9CA1CA2ALOX5 | |
| SCHEMBL11491896 | 0.84 | MAOB (0.48) | TNKSMAOBCA9CA1CA2 | |
| SCHEMBL11491895 | 0.84 | MAOB (0.48) | TNKSMAOBCA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217301-A | Cyano-substituted stilbene compounds | CIBA-GEIGY CORPORATION (US) | 1980-08-12 | — | — | US | disclosed |
| US-4097515-A | Process for the manufacture of cyano-substituted stilbene compounds | CIBA-GEIGY CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4008224-A | OPTICAL BRIGHTENER | CIBA-GEIGY CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |