⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513007 | 0.74 | — | — | |
| SCHEMBL7380608 | 0.73 | — | — | |
| SCHEMBL28493181 | 0.71 | — | — | |
| SCHEMBL1721292 | 0.71 | — | — | |
| SCHEMBL23223078 | 0.71 | — | — | |
| SCHEMBL8535119 | 0.68 | — | — | |
| SCHEMBL231964 | 0.66 | SLC18A3 (0.32) | — | |
| SCHEMBL3828819 | 0.65 | SLC18A3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL28354165 | 0.65 | SLC18A3 (0.31) | — | |
| SCHEMBL8514658 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000306-B1 | SUBSTITUTED HEXAHYDROBENZOPYRANO(3,2-C)PYRIDINES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-05-28 | — | — | EP | claimed |
| US-4201783-A | Antidepressant substituted hexahydro benzopyrano [3,2-c] pyridines | LIPHA LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-05-06 | — | — | US | claimed |
| EP-0000306-B1 | SUBSTITUTED HEXAHYDROBENZOPYRANO(3,2-C)PYRIDINES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-05-28 | — | — | EP | disclosed |
| EP-0000306-A1 | Substituted hexahydrobenzopyrano(3,2-c)pyridines, process for their preparation and medicines containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1979-01-10 | — | — | EP | disclosed |