Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11493832 | 0.91 | CHRM1 (0.46) | PTGS1CHRM1ITGB1ITGA4ITGB7 | |
| SCHEMBL11496178 | 0.89 | CHRM1 (0.44) | PTGS1CHRM1APPITGB1ITGA4 | |
| SCHEMBL11490242 | 0.88 | CHRM1 (0.43) | PTGS1CHRM1ITGB1ITGA4ITGB7 | |
| SCHEMBL11488823 | 0.87 | PTGS1 (0.56) | PTGS1CHRM1AKR1C3AKR1C2APP | |
| SCHEMBL11490189 | 0.87 | PTGS1 (0.44) | PTGS1CHRM1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL11489116 | 0.87 | CHRM1 (0.43) | PTGS1CHRM1ITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL11493900 | 0.86 | PTGS1 (0.55) | PTGS1CHRM1AKR1C3AKR1C2APP | |
| SCHEMBL11493818 | 0.85 | PTGS1 (0.54) | PTGS1CHRM1AKR1C3AKR1C2APP | |
| SCHEMBL11492532 | 0.85 | CHRM1 (0.41) | PTGS1CHRM1PSEN1PSEN2APH1B | |
| SCHEMBL11489015 | 0.84 | CHRM1 (0.40) | PTGS1CHRM1ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |