⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052821 | 0.67 | — | — | |
| SCHEMBL95826 | 0.61 | — | — | |
| SCHEMBL15742684 | 0.61 | — | — | |
| SCHEMBL5774995 | 0.61 | — | — | |
| SCHEMBL6336081 | 0.61 | — | — | |
| SCHEMBL15742588 | 0.61 | — | — | |
| SCHEMBL9846 | 0.61 | — | — | |
| SCHEMBL3948682 | 0.61 | — | — | |
| Fluoride SCHEMBL4328476 | 0.59 | — | — | |
| SCHEMBL4442194 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153999-A | Novel compounds as cannabinoid receptor-1 inhibitors | AMOREPACIFIC CORP | 2013-06-12 | — | — | CN | claimed |
| CN-103153999-B | Compounds as cannabinoid receptor-1 inhibitors | AMOREPACIFIC CORP. (KR) | 2016-06-01 | — | — | CN | disclosed |
| CN-105153146-A | Novel 3-hydroxyisothiazole 1-oxide derivative | MOCHIDA PHARM CO LTD | 2015-12-16 | — | — | CN | disclosed |
| CN-103517898-B | Novel 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARMACEUTICAL CO.,LTD. (JP) | 2015-09-30 | — | — | CN | disclosed |
| US-20150266839-A1 | CYCLIC AMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-09-24 | — | — | US | disclosed |
| US-9126934-B2 | Process for producing 4-carbonyloxyquinoline derivatives | NIPPON KAYAKU CO., LTD. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20150225392-A1 | CYCLIC AMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-08-13 | — | — | US | disclosed |
| US-9072758-B2 | Cyclic amide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-07-07 | — | — | US | disclosed |
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | disclosed |
| US-9040525-B2 | Cyclic amide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-20110118468-A1 | PROCESS FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREFOR | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2305649-A1 | METHOD FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREOF | Nippon Kayaku Co., Ltd. (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-7880006-B2 | 4-Acetoxy-5-chloro-6-(4-chlorophenoxy)-2,3-dimethyl-quinoline, used as agricultural and horticultural insecticides | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| CN-1993328-B | Quinoline derivative and insecticide containing same as active constituent | MEIJI SEIKA KAISHA | 2010-12-22 | — | — | CN | disclosed |
| US-20070203181-A1 | Quinoline Derivatives And Insecticide Comprising Thereof As Active Ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-08-30 | — | — | US | disclosed |
| CN-1993328-A | Quinoline derivative and insecticide containing same as active constituent | MEIJI SEIKA KAISHA (JP) | 2007-07-04 | — | — | CN | disclosed |
| EP-1780202-A1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA KAISHA LTD. (JP) | 2007-05-02 | — | — | EP | disclosed |
| US-20070060551-A1 | Methods of using isothiazole derivatives to treat cancer or inflammation | QLT, INC. (CA) | 2007-03-15 | — | — | US | disclosed |
| EP-1521577-A1 | METHODS OF USING ISOTHIAZOLE DERIVATIVES TO TREAT CANCER OR INFLAMMATION | QLT, Inc. (CA) | 2005-04-13 | — | — | EP | disclosed |
| WO-2003105843-A1 | METHODS OF USING ISOTHIAZOLE DERIVATIVES TO TREAT CANCER OR INFLAMMATION | KINETEK PHARMACEUTICALS, INC. (CA) | 2003-12-24 | — | — | WO | disclosed |