SCHEMBL1148743

SCHEMBL1148743

ClC1(Cl)[CH]CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2904952 0.75
SCHEMBL23386 0.70
SCHEMBL3209616 0.70
SCHEMBL839877 0.68
SCHEMBL14917295 0.67
SCHEMBL165170 0.64
SCHEMBL478015 0.64
SCHEMBL1920244 0.60
SCHEMBL5573389 0.58
SCHEMBL1318942 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399209-A1 NEW QUINOLINE DERIVATIVES Elanco Animal Health GmbH (DE) 2024-07-17 EP claimed
WO-2023036821-A1 NEW QUINOLINE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2023-03-16 WO claimed
EP-4148052-A1 NEW QUINOLINE DERIVATIVES Bayer Animal Health GmbH (DE) 2023-03-15 EP claimed
EP-4399209-A1 NEW QUINOLINE DERIVATIVES Elanco Animal Health GmbH (DE) 2024-07-17 EP disclosed
CN-117957223-A Quinoline derivatives 礼蓝动物保健有限公司 2024-04-30 CN disclosed
WO-2023036821-A1 NEW QUINOLINE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2023-03-16 WO disclosed
EP-4148052-A1 NEW QUINOLINE DERIVATIVES Bayer Animal Health GmbH (DE) 2023-03-15 EP disclosed
EP-3636651-A1 HEXAHYDROPYRAZINOBENZ- OR -PYRIDO-OXAZEPINES CARRYING AN OXYGEN-CONTAINING SUBSTITUENT AND USE THEREOF IN THE TREATMENT OF 5-HT2C-DEPENDENT DISORDERS AbbVie Deutschland GmbH & Co. KG (DE) 2020-04-15 EP disclosed
US-20190135777-A1 QUINOLINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO THE MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR AbbVie Deutschland GmbH & Co. KG (DE) 2019-05-09 US disclosed
US-10160744-B2 Quinoline compounds suitable for treating disorders that respond to the modulation of the serotonin 5-HT6 receptor AbbVie Deutschland GmbH & Co. KG (DE) 2018-12-25 US disclosed
US-20180339996-A1 HEXAHYDROPYRAZINOBENZ- OR -PYRIDO-OXAZEPINES CARRYING AN OXYGEN-CONTAINING SUBSTITUENT AND USE THEREOF IN THE TREATMENT OF 5-HT2C-DEPENDENT DISORDERS AbbVie Deutschland GmbH & Co. KG (DE) 2018-11-29 US disclosed
US-20050176784-A1 Malononitrile compounds and their use as pesticides SUMITOMO CHECMICAL COMPANY, LIMITED (JP) 2005-08-11 US disclosed
CN-1648122-A Malononitrile compounds and its use SUMITOMO CHEMICAL CO (JP) 2005-08-03 CN disclosed
WO-2005068432-A1 MALONONITRILE COMPOUND AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-28 WO disclosed
EP-1555259-A1 Malononitrile compounds as pesticides Sumitomo Chemical Company, Limited (JP) 2005-07-20 EP disclosed
EP-1521528-A1 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES Sumitomo Chemical Company, Limited (JP) 2005-04-13 EP disclosed
US-20040143007-A1 Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-07-22 US disclosed
EP-1392647-A1 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-03-03 EP disclosed
WO-2004006677-A1 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-01-22 WO disclosed
WO-2002090321-A1 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-11-14 WO disclosed