Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603164 | 0.89 | AKT1 (0.40) | AKT1MEN1KMT2AADRB2UTS2R | |
| SCHEMBL11489175 | 0.86 | SMN1; SMN2 (0.44) | AKT1MEN1KMT2A | |
| SCHEMBL11493561 | 0.86 | FFAR1 (0.39) | MEN1KMT2AUTS2R | |
| SCHEMBL11494299 | 0.85 | AKT1 (0.50) | AKT1MEN1KMT2AADRB2UTS2R | |
| SCHEMBL11489646 | 0.85 | GRIA4 (0.46) | ADRB2 | |
| SCHEMBL11606556 | 0.83 | MAPK1 (0.38) | MEN1KMT2AKDM4E | |
| SCHEMBL11496377 | 0.83 | SLC6A4 (0.45) | AKT1ADRB2UTS2RFFAR2 | |
| SCHEMBL11492694 | 0.82 | HTT (0.48) | AKT1MEN1KMT2AUTS2RKDM4E | |
| SCHEMBL11489472 | 0.82 | AKT1 (0.44) | AKT1KMT2AADRB2UTS2R | |
| SCHEMBL11494123 | 0.81 | UTS2R (0.47) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |