Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790470 | 0.88 | KDM1A (0.46) | — | |
| SCHEMBL9790466 | 0.88 | KDM1A (0.46) | — | |
| SCHEMBL9790462 | 0.88 | KDM1A (0.46) | — | |
| SCHEMBL5525240 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTL3MBTL1WDR5HPGD | |
| SCHEMBL6496296 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTL3MBTL1WDR5HPGD | |
| SCHEMBL5525241 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTL3MBTL1WDR5HPGD | |
| Hydrochloric Acid SCHEMBL9790505 | 0.86 | KDM1A (0.44) | — | |
| Hydrochloric Acid SCHEMBL9790500 | 0.86 | KDM1A (0.44) | — | |
| Hydrochloric Acid SCHEMBL9790508 | 0.86 | KDM1A (0.44) | — | |
| SCHEMBL11486493 | 0.83 | BCL2L1 (0.42) | SMN1; SMN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |