Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543533 | 0.89 | DNMT3A (0.72) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11363928 | 0.87 | DNMT3A (0.72) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL14363139 | 0.86 | DNMT3A (0.78) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL30381560 | 0.86 | HDAC1 (0.79) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11481071 | 0.86 | HDAC1 (0.79) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL3784241 | 0.85 | DNMT3A (0.80) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL8261934 | 0.85 | DNMT3A (0.84) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL8981792 | 0.85 | DNMT3A (0.72) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11471216 | 0.84 | DNMT3A (0.75) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11487522 | 0.84 | DNMT3A (0.75) | DNMT3AHDAC1HDAC6NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238506-A | SECONDARY OR TERTIARY AMIDE-SUBSTITUTED | BOEHRINGER MANNHEIM GMBH (DE) | 1980-12-09 | — | — | US | claimed |
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | disclosed |
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | disclosed |
| US-4113871-A | HYPOGLYCEMICALLY AND HYPOLIPIDEMICALLY ACTIVE DERIVATIVES OF PHENYL-ALKANE-CARBOXYLIC ACIDS | BOEHRINGER MANNHEIM GMBH (DE) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | BACE1, PSEN1, BACE2 | DNMT3A 3271/4885HDAC1 89/4885HDAC6 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.