Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429551 | 1.00 | MAPT (0.58) | MAPTHPGDCYP1A2CYP2C19ALOX12 | |
| SCHEMBL6998661 | 0.81 | MAPT (0.67) | MAPTHPGDCYP1A2CYP2C19ALOX12 | |
| SCHEMBL6998663 | 0.81 | MAPT (0.67) | MAPTHPGDCYP1A2CYP2C19ALOX12 | |
| SCHEMBL9756740 | 0.81 | CYP1A2 (0.58) | MAPTHPGDCYP1A2CYP2C19MAOB | |
| SCHEMBL9756739 | 0.81 | CYP1A2 (0.58) | MAPTHPGDCYP1A2CYP2C19MAOB | |
| SCHEMBL5197269 | 0.80 | RECQL (0.55) | MAPTHPGDMAOBCYP1B1LMNA | |
| SCHEMBL5197267 | 0.80 | RECQL (0.55) | MAPTHPGDMAOBCYP1B1LMNA | |
| SCHEMBL11298787 | 0.79 | F3 (0.64) | MAPTHPGDMAOBMAOACYP1B1 | |
| SCHEMBL9519390 | 0.79 | F3 (0.64) | MAPTHPGDMAOBMAOACYP1B1 | |
| SCHEMBL11625862 | 0.79 | MAPT (0.51) | MAPTHPGDCYP1A2CYP2C19ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018532-A1 | 1-Aryl-4-methyl-penta-1,2-dienes, process for their preparation and their use for the preparation of 3-(2-aryl-vinyl)-2,2-dimethylcyclopropane-1-carboxylates | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |