Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL28263629 | 0.96 | TSHR (0.65) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL11474042 | 0.92 | MEN1 (0.61) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL11350171 | 0.90 | MEN1 (0.64) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL11517767 | 0.90 | MEN1 (0.64) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL11517971 | 0.90 | MEN1 (0.64) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL1868836 | 0.84 | MEN1 (0.55) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL6130638 | 0.84 | MEN1 (0.55) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL6800013 | 0.83 | TSHR (0.62) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL11475009 | 0.83 | TSHR (0.54) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10931986 | 0.82 | MEN1 (0.53) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190727-A | CORROSION INHIBITORS IN DRILLING FLUIDS | PETROLITE CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |