Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401965 | 1.00 | MEN1 (0.31) | MEN1KMT2AHTTL3MBTL1HDAC3 | |
| SCHEMBL4334790 | 1.00 | MEN1 (0.31) | MEN1KMT2AHTTL3MBTL1HDAC3 | |
| SCHEMBL1148520 | 0.98 | MEN1 (0.32) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL167777 | 0.92 | MEN1 (0.33) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL24101 | 0.83 | MEN1 (0.34) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL15263236 | 0.82 | FFAR1 (0.38) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL11060568 | 0.82 | FFAR1 (0.38) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL15569600 | 0.81 | MEN1 (0.33) | MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL2121005 | 0.80 | CHRM2 (0.41) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL22321638 | 0.80 | MEN1 (0.31) | MEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884114-B2 | N-(4-{4-[(6-butyl-8-quinolinyl)oxy]-1-piperidinyl}butyl)ethanesulfonamide for treatment of allergic rhinitis | GLAXO GROUP LIMITED (GB) | 2011-02-08 | — | — | US | disclosed |