⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148261 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL133844 | 0.72 | — | — | |
| SCHEMBL8786973 | 0.71 | — | — | |
| SCHEMBL28240807 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL27455897 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL559533 | 0.69 | — | — | |
| SCHEMBL6428112 | 0.67 | TSHR (0.39) | — | |
| SCHEMBL8465970 | 0.67 | TSHR (0.39) | — | |
| SCHEMBL566203 | 0.67 | — | — | |
| SCHEMBL1149055 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101167697-A | Donepezils compound long-acting slow-releasing and controlled-releasing composition and preparation method thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2008-04-30 | — | — | CN | claimed |
| EP-1780202-B1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |
| CN-101167697-B | Donepezils compound long-acting slow-releasing and controlled-releasing composition and preparation method thereof | SHANGHAI INST MATERIA MEDICA | 2011-03-30 | — | — | CN | disclosed |
| US-7880006-B2 | 4-Acetoxy-5-chloro-6-(4-chlorophenoxy)-2,3-dimethyl-quinoline, used as agricultural and horticultural insecticides | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| CN-101167697-A | Donepezils compound long-acting slow-releasing and controlled-releasing composition and preparation method thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2008-04-30 | — | — | CN | disclosed |
| US-20070203181-A1 | Quinoline Derivatives And Insecticide Comprising Thereof As Active Ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-08-30 | — | — | US | disclosed |
| EP-1780202-A1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA KAISHA LTD. (JP) | 2007-05-02 | — | — | EP | disclosed |