Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22677533 | 0.86 | HDAC3 (0.54) | ABL1HDAC3HDAC1HDAC2PLK1 | |
| SCHEMBL5281377 | 0.86 | HDAC3 (0.54) | ABL1HDAC3HDAC1HDAC2PLK1 | |
| SCHEMBL10432350 | 0.86 | ABL1 (0.49) | ABL1HDAC3HDAC1HDAC2PLK1 | |
| SCHEMBL11935569 | 0.85 | PRSS1 (0.45) | HDAC3HDAC1PRSS1F2PRSS2 | |
| SCHEMBL16439908 | 0.83 | ABL1 (0.59) | ABL1PLK1PRSS1F2PRSS2 | |
| SCHEMBL3395174 | 0.83 | ABL1 (0.59) | ABL1PLK1PRSS1F2PRSS2 | |
| SCHEMBL2720066 | 0.83 | ABL1 (0.59) | ABL1PLK1PRSS1F2PRSS2 | |
| SCHEMBL9506930 | 0.83 | ABL1 (0.59) | ABL1PLK1PRSS1F2PRSS2 | |
| SCHEMBL11476522 | 0.83 | ABL1 (0.59) | ABL1PLK1PRSS1F2PRSS2 | |
| SCHEMBL187892 | 0.83 | ABL1 (0.59) | ABL1PLK1PRSS1F2PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198522-A | HYPOLIPIDEMIC ACND ANTI-ATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-04-15 | — | — | US | disclosed |