⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10177513 | 0.67 | — | — | |
| SCHEMBL10457098 | 0.67 | — | — | |
| SCHEMBL144408 | 0.62 | — | — | |
| SCHEMBL1800841 | 0.59 | — | — | |
| SCHEMBL14580 | 0.59 | — | — | |
| SCHEMBL14330322 | 0.59 | — | — | |
| SCHEMBL10526631 | 0.59 | — | — | |
| SCHEMBL16623329 | 0.59 | — | — | |
| SCHEMBL1680362 | 0.59 | — | — | |
| SCHEMBL312476 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180305400-A1 | STABILIZED COMPOUNDS HAVING SECONDARY STRUCTURE MOTIFS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-10-25 | — | — | US | claimed |
| US-9505801-B2 | Stabilized compounds having secondary structure motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-29 | — | — | US | claimed |
| EP-3762366-A1 | COMPOUNDS FOR INHIBITING PROTEIN DEGRADATION AND METHODS OF USE THEREOF IN THE TREATMENT OF CANCER | Pi Therapeutics Ltd. (IL) | 2021-01-13 | — | — | EP | disclosed |
| US-20200399262-A1 | COMPOUNDS FOR INHIBITING PROTEIN DEGRADATION AND METHODS OF USE THEREOF IN THE TREATMENT OF CANCER | PI THERAPEUTICS LTD (IL) | 2020-12-24 | — | — | US | disclosed |
| WO-2019171379-A1 | COMPOUNDS FOR INHIBITING PROTEIN DEGRADATION AND METHODS OF USE THEREOF IN THE TREATMENT OF CANCER | PI THERAPEUTICS LTD. (IL) | 2019-09-12 | — | — | WO | disclosed |
| US-20180305400-A1 | STABILIZED COMPOUNDS HAVING SECONDARY STRUCTURE MOTIFS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-10-25 | — | — | US | disclosed |
| US-9951099-B2 | Stabilized compounds having secondary structure motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170088581-A1 | STABILIZED COMPOUNDS HAVING SECONDARY STRUCTURE MOTIFS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-30 | — | — | US | disclosed |
| US-9505801-B2 | Stabilized compounds having secondary structure motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-29 | — | — | US | disclosed |
| US-8895699-B2 | Stabilized compounds having secondary structure motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-11-25 | — | — | US | disclosed |
| US-20140162339-A1 | Stabilized Compounds Having Secondary Structure Motifs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-12 | — | — | US | disclosed |
| US-6770355-B1 | USABLE AS A SUBSTITUTE FOR SOFT VINYL CHLORIDE FILMS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| US-6734270-B1 | Polypropylene-based calendered article and injection-molded article | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2004-05-11 | — | — | US | disclosed |
| US-20040030093-A1 | Metal catalyst for ring-opening polymerization of heterocyclic compound | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1340780-A1 | METAL CATALYST FOR RING-OPENING POLYMERIZATION OF HETEROCYCLIC COMPOUND | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-1241206-A1 | POLYPROPYLENE FILM AND MULTILAYERED LAMINATE | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-09-18 | — | — | EP | disclosed |
| CN-1367247-A | Heavy metal toxinicide, its preparation method and application | UNIV FUDAN (CN) | 2002-09-04 | — | — | CN | disclosed |
| EP-1231236-A1 | POLYPROPYLENE FILM AND MULTILAYERED LAMINATE | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-1231226-A1 | ROLLED POLYPROPYLENE AND INJECTION-MOLDED POLYPROPYLENE | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-4471107-A | Process for the prepartion of vinylpolystyrylpyridine compounds | AMERICAN CYANAMID COMPANY (US) | 1984-09-11 | — | — | US | disclosed |