Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114999 | 0.91 | PIK3CA (0.56) | PIK3CAMTOR | |
| SCHEMBL114801 | 0.90 | PIK3CA (0.54) | PIK3CAMTOR | |
| SCHEMBL3106178 | 0.83 | PIK3CA (0.85) | PIK3CAMTOR | |
| SCHEMBL116972 | 0.83 | PIK3CA (0.85) | PIK3CAMTOR | |
| SCHEMBL116179 | 0.77 | PIK3CA (0.82) | PIK3CAMTOR | |
| SCHEMBL113476 | 0.76 | PIK3CA (0.64) | PIK3CAMTOR | |
| SCHEMBL7777565 | 0.75 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL7779004 | 0.75 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL7776772 | 0.75 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL115700 | 0.75 | PIK3CA (0.63) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424859-A1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | Amgen, Inc (US) | 2012-03-07 | — | — | EP | claimed |
| WO-2010126895-A1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | AMGEN INC. (US) | 2010-11-04 | — | — | WO | claimed |
| EP-2424859-A1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | Amgen, Inc (US) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010126895-A1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | AMGEN INC. (US) | 2010-11-04 | — | — | WO | disclosed |