Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13338391 | 1.00 | UGT2B7 (0.46) | UGT2B7KDM4EHTTALDH1A1MAPT | |
| SCHEMBL17468070 | 0.95 | KDM4E (0.42) | UGT2B7KDM4EHTTALDH1A1MAPT | |
| SCHEMBL13338354 | 0.94 | UGT2B7 (0.50) | UGT2B7KDM4EHTTKMT2ANPC1 | |
| SCHEMBL13338438 | 0.91 | UGT2B7 (0.42) | UGT2B7KDM4EHTTALDH1A1MAPT | |
| SCHEMBL13338436 | 0.89 | HTT (0.54) | UGT2B7KDM4EHTTALDH1A1NPC1 | |
| SCHEMBL13338430 | 0.88 | HTR2C (0.42) | UGT2B7KDM4EHTTNPC1RAB9A | |
| SCHEMBL13338432 | 0.87 | CYP1A2 (0.48) | UGT2B7KDM4EHTTMAPTLMNA | |
| SCHEMBL13338426 | 0.87 | ESR1 (0.47) | UGT2B7KDM4EHTTALDH1A1MAPT | |
| SCHEMBL13338464 | 0.87 | ESR1 (0.47) | UGT2B7KDM4EHTTNPC1RAB9A | |
| SCHEMBL13338446 | 0.87 | UGT2B7 (0.42) | UGT2B7KDM4EHTTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014998-A1 | Preparation of tertiary aromatic amines by reductive alkylation of diaryl secondary amines with ketones | UNIROYAL, INC. (US) | 1980-09-03 | — | — | EP | disclosed |