Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | EED | O75530 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HLA-A | P04439 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11486433 | 0.99 | SSTR5 (0.42) | SSTR5ALDH1A1GFERMEN1KMT2A | |
| SCHEMBL11499454 | 0.91 | HDAC6 (0.44) | SSTR5ALDH1A1MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL11470685 | 0.90 | HDAC6 (0.43) | SSTR5ALDH1A1MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL11471583 | 0.87 | HDAC6 (0.42) | SSTR5ALDH1A1MEN1KMT2AHTR6 | |
| SCHEMBL11479748 | 0.86 | HDAC6 (0.44) | MEN1KMT2ACYP1A2ABCB1MAPT | |
| Hydrochloric Acid SCHEMBL11467252 | 0.85 | HDAC6 (0.43) | ALDH1A1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL11475559 | 0.84 | DCUN1D1 (0.41) | ALDH1A1GAATP53CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL11468675 | 0.83 | DCUN1D1 (0.40) | ALDH1A1GAATP53CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL11479030 | 0.81 | HDAC6 (0.41) | ALDH1A1KMT2AHTR6GAASIGMAR1 | |
| SCHEMBL11470640 | 0.80 | HDAC8 (0.42) | ALDH1A1MEN1KMT2ATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181657-A | 2-Aminooctahydroindolo[2,3-a]quinolizines useful in treating cardiovascular disorders | MILES LABORATORIES, INC. (US) | 1980-01-01 | — | — | US | disclosed |