Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501462 | 0.77 | SMN1; SMN2 (0.45) | POLBCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29204421 | 0.73 | CYP1A2 (0.53) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28027778 | 0.73 | ESR1 (0.50) | ESR1ESR2POLBCYP1A2CYP3A4 | |
| SCHEMBL28811029 | 0.73 | ESR1 (0.50) | ESR1ESR2POLBCYP1A2CYP3A4 | |
| SCHEMBL27500599 | 0.73 | KDM4E (0.53) | ESR1ESR2POLBCYP1A2CYP3A4 | |
| SCHEMBL27872521 | 0.73 | ESR1 (0.50) | ESR1ESR2POLBCYP1A2CYP3A4 | |
| SCHEMBL11501463 | 0.73 | ESR1 (0.58) | ESR1ESR2POLBCYP3A4CYP2C19 | |
| SCHEMBL29514776 | 0.73 | ESR1 (0.73) | ESR1ESR2POLBCYP1A2CYP3A4 | |
| SCHEMBL194068 | 0.73 | ESR1 (0.73) | ESR1ESR2POLBCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL29204422 | 0.72 | CYP1A2 (0.51) | ESR1ESR2CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244954-A | Acridine compounds and methods of combatting viruses with them | STERLING DRUG INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4150134-A | Aminoalkoxy substituted 9(aryl or aralkyl)-acridines | STERLING DRUG INC. (US) | 1979-04-17 | — | — | US | disclosed |