SCHEMBL11501467

SCHEMBL11501467

ClC(Cl)Oc1[c]cccc1.Oc1cccc(Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
KIF11 P52732 1/20 0.31
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1005299 0.80
SCHEMBL134755 0.71
SCHEMBL30631964 0.71
2-Chlorophenol SCHEMBL9056963 0.69 TSHR (0.85) TSHRALDH1A1CYP3A4MAPK1KIF11
SCHEMBL31006506 0.69 TSHR (0.94) TSHRALDH1A1CYP3A4MAPK1KIF11
SCHEMBL5842280 0.69 TSHR (0.94) TSHRALDH1A1CYP3A4MAPK1KIF11
SCHEMBL31252200 0.69 TSHR (0.94) TSHRALDH1A1CYP3A4MAPK1KIF11
SCHEMBL30091824 0.69 TSHR (0.94) TSHRALDH1A1CYP3A4MAPK1KIF11
Hydrochloric Acid SCHEMBL9797291 0.69 TSHR (0.94) TSHRALDH1A1CYP3A4MAPK1KIF11
Ammonia Solution, Strong SCHEMBL29156113 0.69 TSHR (0.94) TSHRALDH1A1CYP3A4MAPK1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4216342-A Process for the purification of crude 2,4,5-trichlorophenol GIVAUDAN CORPORATION (US) 1980-08-05 US disclosed