Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10268948 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1LMNAHTTPOLB | |
| SCHEMBL21727237 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1LMNAHTTPOLB | |
| SCHEMBL12909388 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1LMNAHTTPOLB | |
| SCHEMBL11501519 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1LMNAHTTPOLB | |
| SCHEMBL2904322 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1LMNAHTTPOLB | |
| SCHEMBL22642035 | 0.96 | KDM4E (0.44) | KDM4EALDH1A1LMNAHTTPOLB | |
| SCHEMBL9197226 | 0.92 | — | — | |
| SCHEMBL5481927 | 0.92 | — | — | |
| SCHEMBL15062108 | 0.92 | — | — | |
| SCHEMBL772885 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107688069-B | Method for detecting (1R,2R) -cyclohexane-1, 2-dimethanol | 顾世海 | 2020-11-03 | — | — | CN | claimed |
| CN-107688069-B | Method for detecting (1R,2R) -cyclohexane-1, 2-dimethanol | 顾世海 | 2020-11-03 | — | — | CN | disclosed |
| EP-2917185-B1 | SULFOXIMINE SUBSTITUTED QUINAZOLINES FOR PHARMACEUTICAL COMPOSITIONS | EVOTEC INT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-20170088583-A1 | MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS | ENANTA PHARM INC (US) | 2017-03-30 | — | — | US | disclosed |
| US-9220748-B2 | Macrocyclic proline derived HCV serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-20140194350-A1 | MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| WO-2014072244-A1 | SULFOXIMINE SUBSTITUTED QUINAZOLINES FOR PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-15 | — | — | WO | disclosed |
| US-4156603-A | COMPLEXED WITH A POLYFUNCTIONAL LEWIS BASE | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4147530-A | Reductions of inorganic substrates with chelated sodium hydridoaluminates or hydridoborates | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4088666-A | Reductions with chelated lithium hydridoaluminates or hydridoborates | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088583-A1 | MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS | PREP, PRSS1, PEPD | KDM4E 1290/4885ALDH1A1 1434/4885LMNA 3069/4885 |
| US-20140194350-A1 | MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS | PREP, PRSS1, PEPD | KDM4E 1290/4885ALDH1A1 1434/4885LMNA 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.