Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23454433 | 0.91 | CRBN (0.41) | CRBNLMNATSHRNFKB1CYP1A2 | |
| SCHEMBL17198966 | 0.82 | — | — | |
| SCHEMBL11922967 | 0.80 | CRBN (0.39) | CRBNLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL11151241 | 0.80 | CRBN (0.43) | CRBNLMNATSHRNFKB1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11303450 | 0.80 | — | — | |
| SCHEMBL146394 | 0.79 | — | — | |
| SCHEMBL2746380 | 0.78 | CRBN (0.42) | CRBNTAS2R38 | |
| SCHEMBL27939070 | 0.76 | CRBN (0.60) | CRBNLMNATSHRNFKB1CYP1A2 | |
| SCHEMBL15045 | 0.76 | — | — | |
| SCHEMBL27524722 | 0.76 | CRBN (0.60) | CRBNLMNATSHRNFKB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | disclosed |
| US-4163022-A | ANTIPLAQUE AGENTS | COOPER LABORATORIES, INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4115448-A | Carbamylguanidine antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4115447-A | Carbamylguanidine antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | disclosed |
| US-4022962-A | DENTAL PLAQUE INHIBITORS | COOPER LABORATORIES, INC. (US) | 1977-05-10 | — | — | US | disclosed |