SCHEMBL11502811

SCHEMBL11502811

CCC(C)C(N)C(O)C=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
GAPDH P04406 1/20 0.32
LAP3 P28838 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13176948 0.80
SCHEMBL4044143 0.80
SCHEMBL21000990 0.75
SCHEMBL21000991 0.75
SCHEMBL6120976 0.73
SCHEMBL24389269 0.72
SCHEMBL21843042 0.72
SCHEMBL10412690 0.72
SCHEMBL14617610 0.72
SCHEMBL13416207 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4167448-A AMASTATINS A1, A2, A3, B1 AND B2 PRODUCED BY AEROBIC CULTIVATION OF STREPTOMYCES ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1979-09-11 US claimed
US-4126606-A CONTAINING VALINE, AMASTATINS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1978-11-21 US claimed
JP-54024845-A None JP disclosed
US-4167448-A AMASTATINS A1, A2, A3, B1 AND B2 PRODUCED BY AEROBIC CULTIVATION OF STREPTOMYCES ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1979-09-11 US disclosed
JP-S5424845-A NOVEL BIO-ACTIVE PEPTIDE AND ITS DERIVATIVE MICROBIAL CHEM RES FOUND 1979-02-24 JP disclosed
US-4126606-A CONTAINING VALINE, AMASTATINS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1978-11-21 US disclosed