Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980 | 0.96 | — | — | |
| SCHEMBL27764889 | 0.92 | — | — | |
| Fluoride SCHEMBL73857 | 0.92 | — | — | |
| SCHEMBL28154308 | 0.92 | — | — | |
| Fluoride SCHEMBL1025919 | 0.92 | — | — | |
| Chloromethane SCHEMBL29210875 | 0.92 | — | — | |
| Methane SCHEMBL28271988 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL4950713 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL366445 | 0.92 | — | — | |
| Bromide SCHEMBL118819 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230038687-A1 | METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS | GENEVANT SCIENCES GMBH (CH) | 2023-02-09 | — | — | US | disclosed |
| CN-114642735-A | Methods, compositions and systems for delivering therapeutic and diagnostic agents into cells | 菲泽尔克斯公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-107530436-B | Methods, compositions and systems for delivering therapeutic and diagnostic agents into cells | 菲泽尔克斯公司 | 2022-03-29 | — | — | CN | disclosed |
| US-11219634-B2 | Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells | GENEVANT SCIENCES GMBH (CH) | 2022-01-11 | — | — | US | disclosed |
| US-20180221402-A1 | METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS | ROIVANT SCIENCES LTD. (GB) | 2018-08-09 | — | — | US | disclosed |
| EP-3247328-A1 | METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS | PhaseRx, Inc. (US) | 2017-11-29 | — | — | EP | disclosed |
| WO-2016118697-A9 | METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS | PHASERX, INC. (US) | 2016-09-29 | — | — | WO | disclosed |
| WO-2016118697-A1 | METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS | PHASERX, INC. (US) | 2016-07-28 | — | — | WO | disclosed |
| CN-102686635-B | Curing accelerators for anaerobically curable compositions | HENKEL CORP. (US) | 2014-10-22 | — | — | CN | disclosed |
| US-8481659-B2 | Cure accelerators for anaerobic curable compositions | HENKEL CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| CN-102686635-A | Curing accelerators for anaerobically curable compositions | HENKEL CORP | 2012-09-19 | — | — | CN | disclosed |
| US-20120157641-A1 | CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS | LOCTITE (R&D) LIMITED (IE) | 2012-06-21 | — | — | US | disclosed |
| EP-2424918-A2 | CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS | Henkel Corporation (US) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010127055-A2 | CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS | HENKEL CORPORATION (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2001007013-A9 | THIOAMIDE MOIETY-CONTAINING POLYMER DRUG CONJUGATES | UNIV NEW JERSEY MED (US) | 2002-11-14 | — | — | WO | disclosed |
| US-6468522-B1 | Controlled release of thioamide moiety-containing therapeutic agents | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2002-10-22 | — | — | US | disclosed |
| US-20020122785-A1 | Materials and processes for controlled release of thioamide moiety-containing therapeutic agents by linking to thiol-containing polymers | STEIN STANLEY (US) | 2002-09-05 | — | — | US | disclosed |
| WO-2001007013-A2 | THIOAMIDE MOIETY-CONTAINING POLYMER DRUG CONJUGATES | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2001-02-01 | — | — | WO | disclosed |