SCHEMBL11504264

SCHEMBL11504264

COC(=O)C(C)C1NCCO1

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
SLC6A3 Q01959 6/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 1/20 0.31
DHFR P00374 1/20 0.31
HTT P42858 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6629635 0.78
SCHEMBL28329006 0.77
SCHEMBL11505237 0.76 ELANE (0.39) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
Hydrochloric Acid SCHEMBL21838844 0.71 SLC6A2 (0.43) SLC6A3SLC6A2SLC6A4
SCHEMBL18040205 0.70
SCHEMBL3128043 0.70
SCHEMBL5268911 0.69
SCHEMBL15302353 0.69
SCHEMBL14105458 0.69
SCHEMBL20969513 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4180645-A Polyurethane coating compositions from dicyclopentenyl acrylate and/or methacrylate ROHM AND HAAS COMPANY (US) 1979-12-25 US disclosed
US-4178425-A USED IN PAINTS, VARNISHES, ADHESIVES, AND BINDERS ROHM AND HAAS COMPANY (US) 1979-12-11 US disclosed
US-4097677-A INTERMEDIATES FOR ADDITION POLYMERS USED IN COATING AND MOLDING PROCESSES ROHM AND HAAS COMPANY (US) 1978-06-27 US disclosed
US-4046744-A Thermosetting coatings based on ketoxime-blocked isocyanates and oxazolidines ROHM AND HAAS COMPANY (US) 1977-09-06 US disclosed