Paraben

Paraben

SCHEMBL11510587

CCCCCc1ccc(O)cc1.O=C(O)c1ccc(O)cc1

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.78
ALDH1A1 P00352 3/20 0.76
MEN1 O00255 1/20 0.76
RARA P10276 1/20 0.76
MAPT P10636 1/20 0.76
MTOR P42345 1/20 0.76
KMT2A Q03164 1/20 0.76
ESR1 P03372 2/20 0.70
ADRA2A P08913 2/20 0.70
ADORA3 P0DMS8 2/20 0.70
TACR2 P21452 2/20 0.70
SLC6A2 P23975 2/20 0.70
SLC6A4 P31645 2/20 0.70
SLC6A3 Q01959 2/20 0.70
KDM4E B2RXH2 1/20 0.70
LMNA P02545 1/20 0.70
SHBG P04278 1/20 0.70
TP53 P04637 1/20 0.70
CYP3A4 P08684 1/20 0.70
HSPD1 P10809 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290118 0.93 RARB (0.89) RARBALDH1A1MEN1RARAMAPT
Hydrochloric Acid SCHEMBL6557514 0.91 RARB (0.86) RARBALDH1A1MEN1RARAMAPT
SCHEMBL1164529 0.91 RARB (0.90) RARBALDH1A1MEN1RARAMAPT
SCHEMBL82569 0.91 RARB (0.90) RARBALDH1A1MEN1RARAMAPT
SCHEMBL503506 0.91 RARB (0.90) RARBALDH1A1MEN1RARAMAPT
SCHEMBL970162 0.91 RARB (0.90) RARBALDH1A1MEN1RARAMAPT
SCHEMBL270423 0.91 RARB (0.90) RARBALDH1A1MEN1RARAMAPT
SCHEMBL503648 0.91 RARB (0.90) RARBALDH1A1MEN1RARAMAPT
SCHEMBL18979307 0.91 RARB (0.90) RARBALDH1A1MEN1RARAMAPT
SCHEMBL18979350 0.91 RARB (0.90) RARBALDH1A1MEN1RARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4173545-A Liquid crystal with high negative dielectric anisotropy and mixtures of the same with nematic liquid crystals for improving dynamic scattering in electro-optic devices THOMSON-CSF (FR) 1979-11-06 US disclosed