Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | BLM | P54132 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | PLEC | Q15149 | 2/20 | 0.48 |
| ▸ | AGER | Q15109 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510612 | 0.83 | EGFR (0.53) | EGFRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL11509476 | 0.79 | MAOB (0.46) | EGFRMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11510302 | 0.78 | EGFR (0.72) | EGFRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL10184604 | 0.77 | MEN1 (0.60) | EGFRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL9163440 | 0.73 | EGFR (1.00) | EGFRMAPTALDH1A1HSP90AA1TDP1 | |
| SCHEMBL6795311 | 0.73 | MAPT (0.80) | EGFRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL10055010 | 0.73 | MAPT (0.80) | EGFRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL11512368 | 0.72 | MAPT (0.59) | L3MBTL1MEN1GAAMAPTBLM | |
| SCHEMBL5272368 | 0.72 | BCHE (0.47) | EGFRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL10781073 | 0.69 | MAPT (0.73) | EGFRL3MBTL1MEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |