⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26618186 | 0.77 | — | — | |
| SCHEMBL26618229 | 0.71 | — | — | |
| SCHEMBL2269668 | 0.68 | — | — | |
| SCHEMBL6746865 | 0.63 | — | — | |
| SCHEMBL9460 | 0.62 | — | — | |
| SCHEMBL27801111 | 0.62 | — | — | |
| SCHEMBL5370 | 0.60 | — | — | |
| SCHEMBL1030444 | 0.60 | — | — | |
| SCHEMBL18274517 | 0.60 | — | — | |
| SCHEMBL15732276 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144251-A | PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4092427-A | ANTICOAGULANTS, OXYTOCICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-4070482-A | Prostaglandin antagonists | AYERST, MCKENNA & HARRISON LTD. (CA) | 1978-01-24 | — | — | US | disclosed |
| US-4048329-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048328-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4007171-A | PROSTAGLANDIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |
| US-4004027-A | Prostaglandin antagonists | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-01-18 | — | — | US | disclosed |
| US-3987081-A | ALKYL DERIVATIVES OF PROSTANOIC ACIDS AND PREPARATION THEREOF | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |
| US-3959263-A | Prostaglandin intermediate | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |