Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514456 | 0.85 | MAPT (0.70) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28626457 | 0.83 | MAPT (0.57) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL29101460 | 0.83 | KDM4E (0.57) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL268673 | 0.83 | KDM4E (0.78) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7710784 | 0.81 | CYP1A2 (0.50) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL10436174 | 0.81 | KDM4E (0.75) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6266755 | 0.81 | KDM4E (0.75) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6261878 | 0.81 | MAPT (0.88) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11513224 | 0.80 | KDM4E (0.68) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3421755 | 0.80 | KDM4E (0.68) | KDM4EMAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |